Composition: Each 1 ml. contains:
Trimethoprim 40 mg.
Sulphadiazine Sodium 200 mg.
COLIPRIM injection is a sterile solution formulated as soluble injectable preparation composed of trimethoprim and Sulphadiazine. The action of the combination proved to be bactericidal, whereas the components separately were only bacteriostatic in action.
Sulphonamides act as an analogue for para-aminobenzoic acid, (PABA) which itself a part of the vitamin, folic acid. In organisms that synthesis their own folic acid, sulphonamides as sulphadiazine acts by blocking the synthesis of folic acid. Sulphonamides are active against bacteria but not against higher organisms as bacteria synthetic their own folic acid whereas higher animals or higher organisms obtained folic acid from the diet.
COLIPRIM injection is indicated for the treatment of infections caused by microorganisms, susceptible to trimethoprim and / or Sulphadiazine affecting the respratory urogenital and gastro-intestinal tract.
COLIPRIM injection is a distinctive drug against a wide range of Gram-positive and Gram-negative bacteria such as E. coli, Salmonella, Klebsiella, Brucella, Corynebacterium pyogens, Pasteurella, Staphylococcus, Streplococcus, Enterobacter and Haemophilus.
Dosage and administration:
Horses, cattle, buffaloes & sheep: By intramuscular or slow intravenous administration.
2.5-4 ml/40 kg body weight, daily for 5 days.
Dog & cat: by subcutaneous injection
1 ml/ 8 kg body weight, daily for 5 days
Meat: 10 days.
Milk: 3 days.
Store in a dark place at a temperature below 30ºC.
20, 50 &100 ml amber color glass injection bottle.
FOR VETERINARY USE ONLY